Hyperprolactinaemia causes and manifestation in outpatient practice

Causes of pediatric heart disease in Rasht and its relationship with clinical ‎manifestation and demographic characteristic

Introduction: Heart disease is the fifth cause of death in infants and children and ‎‏%90‏‎ of ‎these causes are related to congenital heart diseases.Nearly‏%20‏‎ of these children experience ‎heart failure and surgery, but life expectancy for these children is increased by palliative and ‎corrective surgeries. Demographic characteristics and clinical sym...

Hyperprolactinaemia.

Hyperprolactinaemia is a frequent cause of reproductive problems encountered in clinical practice. A variety of pathophysiological conditions can lead to hyperprolactinaemia; therefore, pregnancy, drug effects, hypothyroidism and polycystic ovary syndrome should be excluded before investigating for prolactin-secreting pituitary tumours. Prolactinomas are mainly diagnosed in women aged 20-40 yea...

Macroprolactin and hyperprolactinaemia.

The recent report on “macroprolactin and hyperprolactinaemia” is very interesting. Jamaluddin et al. noted that 4.4 % of the patients have macroprolactin and concluded that “macroprolactin is a significant cause of misdiagnosis, unnecessary investigation, and inappropriate treatment.” Similar to many other “macro” phenomenon (macroCK, macroamylase, etc.), the macroprolactin can result in aberra...

Hyperprolactinaemia and Prolactinoma

Pregnancy. Puerperium. Breast stimulation. Stress physical (including excessive exercise) or psychological including venepuncture. Macroprolactinaemia: This refers to prolactin of high molecular mass, mostly complexes of monomeric prolactin with immunoglobulins (prolactin autoantibody complexes). These larger molecules have low bioactivity and a prolonged clearance rate similar to that of immun...

Hyperprolactinaemia in primary Sjögren's syndrome.